Hepatitis B Virus Prevalence among Patients Attending at Christ the King Hospital in Ideato South, Imo State
Asian Journal of Microbiology and Biotechnology, Volume 8, Issue 2,
Page 8-15
DOI:
10.56557/ajmab/2023/v8i28208
Abstract
This study was carried out to determine the prevalence of hepatitis B virus among patients attending Christ the king hospital, Ideato south, Imo state. Blood samples from 300 patients (108 female and 192 male) at the Christ the King hospital in Ogueme Ntueke, Ideato South, Imo state, were collected for the purpose of identifying the hepatitis B surface antigen (HBsAg) using traditional serological methods. Among the 300 patients, 8.3% tested positive for hepatitis B (4.6% female and 10.4% male). [The highest prevalence of the virus was found in the age group (31 - 40), followed by (11 - 20) and (61 - 70) with 0% prevalence, (21- 30) with (5.1%), (41- 50), (51- 60) with (8.5%), and (41-70) with (3.8%). Sharp object use, tattooing, tonsillectomy, circumcision, and other risk factors all contributed to the virus's spread. The study participants at Christ the King Hospital had a significantly higher prevalence of hepatitis as indicated by the p value of 0.005. Thus, it is strongly advised to read health awareness materials and be informed of the risks of getting this infection].
Keywords:
- Prevalence
- hepatitis B virus
- patients
- Ideato south
How to Cite
Excel, D. K., Ihuarulam, O. C., Jessica, E. E., Jude, O. N., Ohalete, C. N., & Nnodim, J. (2023). Hepatitis B Virus Prevalence among Patients Attending at Christ the King Hospital in Ideato South, Imo State. Asian Journal of Microbiology and Biotechnology, 8(2), 8–15. https://doi.org/10.56557/ajmab/2023/v8i28208
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Anaele CC, Emeonye OP, Nwatu MSB, Cosmas SA, Chukwu UJ, Idabor U, Alozie EF. Prevalence of Hepatitis B Virus among Febrile Patient in General Hospital Okigwe, Imo State, Nigeria, Journal of Biosciences and Medicines. 2021;9:12-19.
Okonko AB, Soleye A, Alli JA, Ojezele MO, Udeze AO, Nwanze JC, Adewale O. Seroprevalence of Hbsag Antigenaemia among Patients in Abeokuta, South Western Nigeria. European Journal of Scientific Research. 2010;10(2):40- 46.
Fasola FA, Kotila TR, Akinyemi JO. Trends in Transmission-transmitted Viral Infection from 2001 to 2006 in Ibadan, Nigeria. Intervirology. 2008;51: 427–431
Zage AU1, Waiya SA, Ali M, Garba M, Muhammad AA. Prevalence of Hepatitis B Virus among Patients Diagnosed with Liver Cirrhosis Disease in Kano, Northern Nigeria, ARC Journal of Immunology and Vaccines. 2018;3(1):24 -29
Olayiwola JO, Lanlehin F. Prevalence of Hepatitis B Virus Infection among the Out-patients in Oyo, Oyo State Nigeria. Acta Scientific Microbiology. 2021;4(11): 62-65.
World Health Organization. Prevalence of hepatitis B virus infection in the world by country Ences. 2010;3(5):12 – 17. Available:http://www.who.int/csr/disease/hepatitis/en/
Menéndez-Arias L, Álvarez M, Pacheco B. Nucleoside/nucleotide analog inhibitors of hepatitis B virus polymerase: mechanism of action and resistance". Current Opinion in Virology. 2014;8:1 - 9.
Adabara NU, Ajal OO, Momohjimoh A, Hashimu Z, Agabi AYV . Prevalence of Hepatitis B Virus among Women Attending Antenatal Clinic in the General Hospital, Minna, Niger State. Shiraz E-Medical Journal. 2012;13(1):28-32
Uneke CJ, Ogbu O, Inyama PU, Anyanwu GI, Njoku MO. Prevalence of hepatitis B virus among blood donors and human immunodeficiency virus infected patients in Jos, Nigeria. Mem Inst Oswaldo Cruz. 2005;100(1):13-6.
WHO. Hepatitis B Vaccines? Weekly Epidemiological Record. 2009;100 - 110
Adewole R, Omilabu SA, Ayodele AOS, Gbotolorun OM, Anorue EI. Prevalence of hepatitis B virus surface antigen (HBsAg) in patients attending dental centre of a tertiary hospital (a pilot study, Journal of Medicine and Medical Sciences. 2013;4(7):275 – 279.
Arinze AO, Emeka, Akujuobi C, Miriam-Benigna CA, Akunne IA, Chuka MO, Chisom GC, George UE. Prevalence of Hepatitis B virus Infection Among Cataract Patients in South-East Nigeria, J Ophthalmol Res. 2021;4(3):221-230
Batholomew C. Knowledge, Attitude and Practices (KAP) concerning Hepatitis B among Adolescents in the Upper West Region of Ghana. The Rural Urban Gradient. 2011;2(3):12 - 17
Bekondi C, Olinger CM, Boua N, Talarmin A, Muller CP, Le Faou A, Venard V. Central African Republic is Part of the West African Hepatitis B Virus Genotype E Crescent. J. Clin. Virol. 2007;40:31–37.
Damulak OD, Ogbenna V, Ma’an O, Rufai SD, Kut T, Bodund A. Hepatitis B virus sero-positivity among voluntary blood donors at a centralized blood service centre in Nigeria. International Journal of Medical and Applied Sciences. 2013;2(3):10-18
Eke AA, Uzoamaka AE, Charles IO, Ifeanyichukwu UE, Chukwuanugo O. Prevalence, correlates and pattern of hepatitis B surface antigen in a low resource setting. Virol J. 20118:12-16.
Emechebe GO, Emodi IJ, Ikefuna AN, Ihechukwu GC, Igwe WC. Hepatitis B Virus. A Review of Nigerian Medical Journal. 2014;50:18-22.
Agarry OO, Lekwot GZ. Prevalence of hepatitis B virus and hepatitis C virus in ante-natal patients in Gwagwalada- Abuja, Nigeria. Report and Opinion. 2010;2(7): 48-50.
Ali M, Idrees M, Ali L, Hussain A, Rehman IU, Saleem S, Afzal S, Butt S. Hepatitis B Virus in Pakistan: A Systematic Review of Prevalence, Risk Factors, Awareness Status and Genotypes. Virol. J. 2011;8:102.
Glory BB, Jennifer AO. Prevalence of Hepatitis B Virus among Patients Presenting with Malaria in Port Harcourt, Rivers State, Nigeria, Current Studies in Comparative Education, Science and Technology. 2017;4(1):203-219.
Isa MA, Bello HS, Mustapha A. Mangga HK, Gulani IA, Aisha MA. Prevalence of hepatitis B Virus among students attending University of Maiduguri clinic, Borno, Nigeria. Int. J. Adv. Res. Biol. Sci. 2014;2(1):138–142.
Lemoine M, Nagayam S, Thursz M. Viral Hepatitis in Resource-limited Countries and Access to Antiviral Therapies: Current and Future Challenges. Fut. Virol. 2013;8(4):371–380.
Bouchard MJ, Puro RJ, Wang L, Schneider RJ. Activation and inhibition of cellular calcium and tyrosine kinase signaling pathways identify targets of the HBx protein involved in hepatitis B virus replication. Journal of Virology. 2003; 77(14):7713–9.
Chai N, Chang HE, Nicolas E, Han Z, Jarnik M, Taylor J. Properties of subviral particles of hepatitis B virus. Journal of Virology. 2008;82(16):7812–7.
Berinyuy BE, Alawode RA, Mohammed AB, Babalola BS, Mustapha A, Oshevire RM, Okunlola MB, Lawal A. Prevalence of Hepatitis B Virus in Nigeria: Review Update. Annals of Public Health and Epidemiology. 2019;1(1):1 – 7.
Blumberg BS. Australia antigen and the biology of hepatitis B. Science. 1977;197(4298): 17-19
Locarnini S. Molecular virology of hepatitis B virus. Seminars in Liver Disease. 2004; 24(1):3–10.
Ndako JA, Onwuliri EA, Adelani Akande T, Olaolu DT, Dahunsi SO. Screening for Hepatitis B Surface Antigen (Hbsag) Among Health Care Workers (Hcw) In an Urban Community South, South Nigeria. IJBPAS. 2014;3(3):415 - 425
Ojo OO, Anibijuwon II. Determination of Antibodies to Hepatitis B Virus In Pregnant Women in Akure, Ondo State, Nigeria. Continental Journal of Microbiology. 2009;3:6-10,
Alter MJ . Epidemiology of Viral Hepatitis and HIV Co-Infection. Journal of Hepatology. 2006;13:56-69.
Altiparmak E, Olajumoke OO, Owolabi AD, Titilope AA, Adewumi A. Seroprevalence of hepatitis B e antigen (HBe antigen) and B core antibodies (IgG anti- HBcore and IgM anti-HBcore) among hepatitis B surface antigen positive blood donors at a Tertiary Centre in Nigeria. BMC Res Notes. 20125: 167 – 175.
Anaele CC, Emeonye OP, Nwatu MSB, Cosmas SA, Chukwu UJ, Idabor U, Alozie EF. Prevalence of Hepatitis B Virus among Febrile Patient in General Hospital Okigwe, Imo State, Nigeria, Journal of Biosciences and Medicines. 2021;9:12-19.
Okonko AB, Soleye A, Alli JA, Ojezele MO, Udeze AO, Nwanze JC, Adewale O. Seroprevalence of Hbsag Antigenaemia among Patients in Abeokuta, South Western Nigeria. European Journal of Scientific Research. 2010;10(2):40- 46.
Fasola FA, Kotila TR, Akinyemi JO. Trends in Transmission-transmitted Viral Infection from 2001 to 2006 in Ibadan, Nigeria. Intervirology. 2008;51: 427–431
Zage AU1, Waiya SA, Ali M, Garba M, Muhammad AA. Prevalence of Hepatitis B Virus among Patients Diagnosed with Liver Cirrhosis Disease in Kano, Northern Nigeria, ARC Journal of Immunology and Vaccines. 2018;3(1):24 -29
Olayiwola JO, Lanlehin F. Prevalence of Hepatitis B Virus Infection among the Out-patients in Oyo, Oyo State Nigeria. Acta Scientific Microbiology. 2021;4(11): 62-65.
World Health Organization. Prevalence of hepatitis B virus infection in the world by country Ences. 2010;3(5):12 – 17. Available:http://www.who.int/csr/disease/hepatitis/en/
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