INVESTIGATING THE FORMULATION OF NEW THERAPEUTIC LOTION FOR BURN INJURY
Journal of International Research in Medical and Pharmaceutical Sciences, Volume 16, Issue 2,
Burn injury has been one of the leading causes of accidental death in the world. Thousands suffer from long-term consequences from the lack of effective first-aid treatment. Many commercial burn lotions are not effective, as claimed. So, it should be an alarming issue for developing a burn injury that could alleviate the initial damages to the burn areas.
Burn skins have three acute excruciating problems such as pains, blisters, and skin infections.
The objective of the study was to create a therapeutic burn lotion that might treat those symptoms with lidocaine, sodium dodecyl sulfate, and antibacterial chemical combinations of camomile oil, hydrogen peroxide, and ethyl alcohol. After an emulsion lotion base was created with distilled water and olive oil, the other ingredients were added in sequence and mixed thoroughly to be homogenized. And, the burn injury lotion was tested for moisturization capability, pain-killing strength, blister reduction, and antibacterial strength.
As a result, the microscopic observations demonstrated the emulsion morphology of our burn lotion was good by being evenly distributed with spherical forms. Its relative viscosity was comparable to other commercial lotions. The moisturization ability was confirmed by the minimal weight change in mung bean jelly test. The skin sensations from the light and touch reflex test were reduced using Lumbricus terrestris, and the blister reduction capability was confirmed with the cabbage incubation test. At the same time, its antibacterial strength was verified with the zone of inhibition test using three types of bacteria such as Bacillus subtilis, Rhodospirillum rubrum, and Micrococcus luteus. The study demonstrated that our burn lotion might work effectively for the patient of burn injury.
- Antibacterial strength
- blister reduction
- burn injury
- burn lotion
- pain relieving ability.
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