We have developed an AI based pipeline to estimate body temperature, respiration rate, SOP (Standard Operating Procedure) violation and heart rate. Moreover we have also developed a plan under the management framework, which includes the collection of datasets from Indonesian university, various corporate events, and hospitals in different geographical areas. The dataset collected from different sources are tested and validated to assess the capabilities of the existing models that we have developed over period and further helps to improve the accuracy level. Our screening platform for infectious disease symptom is a quick, noninvasive, no-contact solution that can detect the first-look indication of symptoms. All it takes is a simple walk-through, followed by standing in front of the camera following SOP guidelines. In a few seconds, our AI powered technology identifies if the subject fit for duty or not. We have used datasets from various events, hospitals, labs to shape and validate our model and have also implemented multi-layer model-based 3D Convolutional Networks to detect heart rate, respiration rate and body temperature. We obtained 98.37%, 98.38% and 85% accuracy for temperature, respiration rate and heart rate respectively. These accuracy values are obtained on our testing dataset obtained from multiple events, hospitals and labs.
Background: Nowadays, one of the main ways to manage HIV infection is the use of highly active antiretroviral therapy (HAART). Despite the benefit associated with the use of antiretrovirals, these could have side effects on certain vital body functions such as the liver and kidneys.
Aim of the Study: The main objective of this study was to assess the liver and kidney functions of people living with HIV (PLWHIV) and undergoing highly active antiretroviral therapy at the Bafoussam Regional Hospital (BRH).
Methodology: A cross-sectional study was conducted for three months on 100 HIV-positive patients undergoing HAART at the Regional Hospital of Bafoussam. Sociodemographic, clinical and biological data were recorded for each subject and then analyzed using standard procedures. Liver function was explored by the following biochemical parameters: alanine aminotransferase, aspartate aminotransferase, albumin, total and direct bilirubin. The renal function was explored by measuring the creatinine and the serum uric acid levels. Results: Among the 100 patients who participated in the study, 83 were women (83 %) and 17 patients were men (17 %). The most represented age group was between 41 and 50 years old (37 %). The mean age was 47.66 ± 10.2 years. For the liver function assessment, 6 % had elevated alanine aminotransferase activity (greater than 42 IU/L), 8 % had an increase in the aspartate aminotransferase activity (greater than 38 IU/L) and 17% of patients had hypoalbuminemia (below 35 g/L). In addition, 14% of the patients had a high total bilirubin level (greater than 1 mg/dL) and 62% of the patients had a high direct bilirubin level (greater than 0.3 mg/dL). Patients presenting simultaneously an abnormal level of direct and total bilirubin were following the Zidovudine-Lamivudine-Atazan avir-Ritonavir (ZLAR) second line regimen. For the evaluation of renal function, 18% had a high creatinine level (greater than 14 mg/L) and 24% of patients had an abnormal level of uric acid (greater than 60 mg/L), this variation was not associated with antiretroviral treatment (p > 0.05).
Conclusion: No significant association was found between the regimen and the variations of certain biochemical parameters. However, compared to ZLAR, Tenofovir-Lamivudine-Dolutegravir (TLD) was the regimen that recorded the largest number of patients with abnormal variations of biochemical parameters involved in this study.
The prevalence of some pathogenic bacteria in retailed meats is becoming a major challenge to human health. The main factor contributing to the contamination of retailed meats, especially in Africa, is poor hygienic practices amongst meat vendors. Poor personal hygiene amongst food handlers coupled with the improper handling of meat could result in its contamination. This study reviewed the prevalence and antibiogram of Salmonella species, Staphylococcus aureus and Shigella species isolated from retailed meats sold in Ihiala town. 50 raw meat samples (25 beef and 25 chicken) were used, they were homogenized in a buffer and inoculated in two selective media (SSA and MSA). The bacterial isolates were further identified after various biochemical tests. It was observed that Staphylococcusaureus occurred more (45.3%) in the samples used, also the beef samples were seen to contain more microorganisms than the chicken samples. After the Antibiotics susceptibility test, it was discovered that Staphylococcusaureus, Shigella species and Salmonella species were resistant to some antibiotics. It is therefore expedient that meat vendors take caution when handling meats, so as to prevent meats from being contaminated with these drug resistant bacteria, thereby preventing health challenges.
Alzheimer's disease (AD) is a disorder of brain which progressively weakens the cognitive function. It is occur due to formation of β amyloid plaques & neurofibrillary tangles, & cholinergic neurotransmitter degeneration. At present there is no cure for this disease but currently it can be controlled by using a drugs which symptomatically treat the AD involve N-methyl D-aspartate (NMDA) receptor antagonist (memantine) & Acetylcholinesterase inhibitors (AChEIs) (donepezil, rivastigmine, galantamine). Natural treatment comprising various medicinal plants & herbs are utilize to treat brain disorders like dementia, amnesia, and AD from ancient time. Preclinical & clinical studies both are confirmed the therapeutic potential of herbal product for inhibition of AD. Medicinal plants shown effectiveness against Alzheimer’s probably because of their pleiotropic & multiple action which involves antioxidants, anti-inflammatory & neuroprotective activity. In this present review we focuses on the therapeutic potential of various medicinal plants which significantly contributed for treating AD & memory deficits.
Propolis is a resinous compound with a balsamic aroma and a sticky consistency that is harvested from the exudates, flowers, and buds of several plants. These biological effects are tied to the phenolic chemicals found in propolis, the structure and concentration of which change depending on the region of production, the variety of plant resins available, the genetic makeup of the queen bee, the technique of production, and the time of year. Biomolecules isolated from plants have the potential to serve as the basis for anticancer medication prototypes with the ability to suppress tumour growth. The structure and concentration of propolis' phenolic compounds vary on the place of production, the range of plant resins accessible, the queen bee's genetic makeup, the manufacturing method, and the season. Plant biomolecules may be used to develop anticancer drugs that inhibit tumour growth. Tropical and subtropical regions are good for bioprospecting due of their biodiversity. Learning about these chemicals' efficacy is crucial since they could be utilised as adjuvants with other drugs or as new cancer treatments. Bee propolis is an important anticancer medication, but more preclinical and clinical research is needed to determine its selectivity, efficacy, and safety. We emphasised on the importance of bee propolis as an anticancer drug and focusing on the chemical components and biological processes.
