SPONTANEOUS PERFORATION OF PRIMARY GASTRIC MALT LYMPHOMA: A CASE REPORT

Main Article Content

MOHAMED HAJRI
WAEL FERJAOUI
GHOFRANE TALBI
DHOUHA BACHA
LASAAD GHARBI
MOHAMED TAHER KHALFALLAH

Abstract

Primary gastric lymphoma with spontaneous perforation is exceptional. We report here the case of a 35- year-old-woman who was admitted to our surgery department with severe epigastralgia. Chest Radiography in standing position showed pneumoperitoneum. Intraoperative exploration revealed a perforated gastric tumor in the greater curvature. A total gastrectomy with lymph node dissection was done. Pathological examination confirmed the diagnosis of extra nodal marginal zone lymphoma of mucosa-associated lymphoid tissue (MALT lymphoma). The patient was referred for postoperative adjuvant chemotherapy. He is currently with no signs of recurrence, 7 months after his operation.

Keywords:
Spontaneous perforation, gastric lymphoma, ulcer

Article Details

How to Cite
HAJRI, M., FERJAOUI, W., TALBI, G., BACHA, D., GHARBI, L., & KHALFALLAH, M. T. (2021). SPONTANEOUS PERFORATION OF PRIMARY GASTRIC MALT LYMPHOMA: A CASE REPORT. Journal of Disease and Global Health, 14(3), 38-42. Retrieved from https://ikppress.org/index.php/JODAGH/article/view/7544
Section
Case Report

References

Nakamura S, Delabie J. Extranodal marginal zone lymphoma of mucosa-associated lymphoid tissue (MALT lymphoma) involving the digestive tract. (Eds.): WHO Classification of Tumours of Digestive System. IARC: Lyon 2019;378- 382.

Nagtegaal ID, Odze RD, Klimstra D, et al. The 2019 WHO classification of tumours of the digestive system. Histopathology. 2020;76: 182–188.

Ruskoné-Fourmestraux A, Lavergne-Slove A, Delmer A. Les lymphomes gastro-intestinaux. /data/revues/03998320/00260003/233/, Available:https://www.em-consulte.com/en/article/99049 (2008, accessed 12 April 2020).

Swerdlow SH. WHO classification of tumours of haematopoietic and lymphoid tissues. WHO Classification of Tumours. 2008;22008:439.

Lepage C, Bouvier A-M, Manfredi S, et al. Incidence and management of primary malignant small bowel cancers: a well-defined French population study. American Journal of Gastroenterology. 2006;101:2826–2832.

DELCHIER J-C. Le lymphome gastrique du MALT, une infection maligne potentiellement curable par l’éradication de Helicobacter pylori. Gastroentérologie Clinique et Biologique. 2003;27:453–458.

Wang Y-G, Zhao L-Y, Liu C-Q, et al. Clinical characteristics and prognostic factors of primary gastric lymphoma: a retrospective study with 165 cases. Medicine; 95.

Nakamura S, Sugiyama T, Matsumoto T, et al. Long-term clinical outcome of gastric MALT lymphoma after eradication of Helicobacter pylori: a multicentre cohort follow-up study of 420 patients in Japan. Gut. 2012;61:507–513.

Miyamoto K, Shimizu Y, Inada K, et al. Mucosa-associated lymphoid tissue lymphoma with perforation of the stomach-A case report. Jpn J Canc Clin. 1999;45:135–41.

Chang Y-T, Huang M-Y, Shih H-H, et al. Gastric MALT lymphoma presented with primary perforation in an adolescent: a case report. BMC pediatrics. 2019;19: 63.

Fischbach W. MALT lymphoma: forget surgery? Digestive Diseases. 2013;31:38–42.

Juárez-Salcedo LM, Sokol L, Chavez JC, et al. Primary Gastric Lymphoma, Epidemiology, Clinical Diagnosis, and Treatment. Cancer Control. 2018;25:1073274818778256.

El Asmar A, Khattar F, Alam M, et al. Spontaneous perforation of primary gastric B‐cell lymphoma of MALT: a case report and literature review. Clinical Case Reports. 2016;4:1049.

López-Zamudio J, Ramírez-González LR, Núnez-Márquez J, et al. Gastric perforation by MALT lymphoma. Case report. Cirugía y Cirujanos (English Edition). 2015;83:217– 221.

Ruskoné-Fourmestraux A, Fischbach W, Aleman B, et al. EGILS consensus report. Gastric extranodal marginal zone B-cell lymphoma of MALT. Gut. 2011;60:747–758.

Zucca E, Copie Bergman C, Ricardi U, et al. Gastric marginal zone lymphoma of MALT type: ESMO Clinical Practice Guidelines for diagnosis, treatment and follow-up.

Ruskoné-Fourmestraux A, Matysiak-Budnik T, Fabiani B, et al. Exclusive moderate-dose radiotherapy in gastric marginal zone B-cell MALT lymphoma: results of a prospective study with a long term follow-up. Radiotherapy and Oncology. 2015;117:178–182.

Chuang S, Diss T, Li C. Primary gastric small lymphocytic lymphoma with perforation. Histopathology. 2006;49:656–658.