Original Research Article

MEDITATION PRACTICE CAN BE EFFECTIVE ON THE SEVERITY OF FATIGUE IN BREAST CANCER PATIENTS UNDERGOING CHEMOTHERAPY

SAMIRA AZGHANDI, POURAN VARVANI FARAHANI, AMIR HOSSEIN KHONSARI, RAYAN NAZMI, HESSAM EDIN TAHERKHANIHA, BAHRAM MOFID

Journal of Disease and Global Health, Page 1-8

Purpose: Due to the prevalence of fatigue in women with breast cancer during chemotherapy and its impact on the psychological state of patients and also the prevalence of depression, they encounter a reduction in life expectancy. This study was aim to determine the effect of meditation on fatigue in breast cancer patients undergoing chemotherapy.

Methods: This randomized clinical trial was conducted on 102 breast cancer patients in two groups. Demographic questionnaire and fatigue severity questionnaire were completed by patients before the intervention. Throughout the intervention, twin hearts meditation was taught to the patients in the experimental group by the experiment fellow and they were asked to perform it at least 3 times a week for two weeks.

Results: Statistically significant differences were observed between the two groups in terms of the fatigue scores before, and after the last intervention in the second weeks. Fatigue severities mean score in the control group changed from (47.3) to (52.4) and the experimental group changed from (49.5) to (35.3).

Conclusions: The meditation exercise reduces the fatigue of breast cancer patients undergoing chemotherapy. Therefore, meditation is recommended as a complementary therapy beside medication in these patients.

Original Research Article

SURVEY STUDY FOR THE ASSESSMENT OF VARIOUS STRESSORS AND THEIR MANAGEMENT AMONG FEMALE STUDENTS OF THE ISLAMIA UNIVERSITY OF BAHAWALPUR, PAKISTAN

LAILA SUMREEN, TAHIRA SHAMIM, GHAZALA SHAHEEN, TEHMINA LIAQAT

Journal of Disease and Global Health, Page 23-31

Purpose of Study: This study aimed to assess the factors that caused stress in female students and student’s preference to overcome the stress.

Study Design: An interviewed based cross-sectional study was conducted at different departments among the female students of The Islamia University Bahawalpur, Pakistan. Sample size of the study was 100. Only chi square test was used. Only female students were preferred.

Results: Majority of students, 65% were between the age group of 18-21 years and 35% were between the ages 22-24 years. Among all the students 59% were hostilities and 41% were day scholars. Most of the students were from BEMS department (36%), BHMS department (33%) and from Pharmacy department (31%). According to percentage distribution, out of 100 students almost 50% suffered from mood swings while majority of them felt lack of concentration due to stress. Most of students found themselves thinking about problems and complained of having no time to spend with their family. All age group students considered hostel life to be a burden and almost half of students were sometimes connected with social media to get rid of stress. Almost 50% students believed that campus environment benefitted them to lower their stress and majority of students responded that social media increased their stress. Many students felt fatigued due to stress even after waking up after adequate sleep and they felt loneliness and homesickness. Some students managed their stress by connecting to social media. Stress affected daily life of either hostellites as well as day scholars in one way or the other.

Study Limitations: Data was collected from just one university that reduced the power of the study.

Practical implications: This study could be helpful in ruling out the stressors and ways to manage the stress in order to overcome the impact of stress on educational and personal life of the students.

Data Articles

A PROSPECTIVE STUDY ON DRUG UTILISATION AND EVALUATION OF ANTI-RETROVIRAL THERAPY AND ANTI-TUBERCULOSIS TREATMENT IN A TERTIARY CARE HOSPITAL

SHAIK MOHAMMED SUHAIL, DIVYA KANDIPALLI, . LAKSHMI, ASHOK C. KUMAR, M. VENU MADHAV REDDY, M. PRAHARSHA LAKSHMI, P. SAMUEL CHANDRA

Journal of Disease and Global Health, Page 9-17

Acquired immune deficiency syndrome is the most serious consequence of infection due to HIV which is a major health problem in public. India is with one sixth of world’s population where one of every eight people is HIV infected. Worldwide, tuberculosis is the common serious infection in HIV infected people. WHO estimated that 13% of 8.7 million individuals who develop incidence tuberculosis are co-infected with HIV. The research followed Prospective Observational Study of Anti-retroviral drugs and Anti-tubercular drugs. The total number of drugs for HIV and TB, were collected from inpatient records, as per the prescription, dose, and route of administration. The study involves the above 18 years old patients and it is planned over 6 months of period in ART CENTER. The demographic data and patient characteristics affected with HIV/AIDS and TB group were enrolled in the study. The analysis of study includes, a total number of 220 prescriptions during the research involving 152 males and 52 females and 16 other patients. The drug utility and evaluation for HIV and TB patients were with ART and ATT and with other poly-pharmacy to improve the immune system that is most important in HIV and TB.

Case Report

KIKUCHI DISEASE-LIKE INFLAMMATORY PATTERN IN SYSTEMIC LUPUS ERYTHEMATOSUS PATIENT: A CASE REPORT

PATARA VORAVUTINON, PAILIN PUANGPET

Journal of Disease and Global Health, Page 18-22

Kikuchi-Fujimoto disease (KFD) is a benign and rare disorder that can be a manifestation of the Kikuchi disease-like inflammatory pattern (KLIP) and coexists with systemic lupus erythematosus (SLE). The corresponding treatment of these diseases is difficult. A 66-year-old Thai man with underlying SLE presented with generalized yellowish erythematous papules and plaques throughout his body. No evidence of fever, lymphadenopathy, or hepatosplenomegaly was noted. Antinuclear antibodies (ANA) were positive but anti-dsDNA, anti-Smith, anti-snRNP, and anti-Ro antibodies were negative. The histopathology was consistent with KFD, and the patient was diagnosed with a Kikuchi disease-like inflammatory pattern. Hydroxychloroquine elicited a rapid and favorable response in the patient who remained relapse-free while on low-dose hydroxychloroquine. Here, we report the case of a 66-year-old Thai man with erythematous plaques on his chest and neck.

Review Article

A DEEP INSIGHT TO NEUROLOGICAL ABNORMALITIES IN COVID – 19: A REVIEW

MUSKAAN BHATIA, MALINI BHATTACHARYYA, BABITA PATNI

Journal of Disease and Global Health, Page 32-42

An ongoing endemic in the China city of Wuhan in the year 2019, December developed a new strain of (SARS-CoV-2) termed Coronavirus 2 similar to SARS CoV.  The emergence of this is not yet known so this endemic seems to be related to severe acute respiratory syndrome (SARS) and Middle East respiratory syndrome coronavirus (MERS-CoV) that are recognised to attack our respiratory system. After the increasing number of cases within the entire planet, World Health Organization revealed SARS-CoV-2 as the epidemic on March 11, 2020. It is seen that the novel virus has affected 140,780,297 people with nearly 3,015,798 deaths across the globe. Some people experience mild to moderate symptoms whereas some fall seriously ill. The infected patients show signs like dry cough, fatigue and fever. Apart from this smell and taste loss was also observed in nearly 70% patients. Hence, neurological manifestations have been observed during covid conditions.