Medicinal Properties in Some Components of Cannabis Species
PLANT CELL BIOTECHNOLOGY AND MOLECULAR BIOLOGY,
Page 17-22
DOI:
10.56557/pcbmb/2023/v24i1-28094
Abstract
Cannabis is a medicinal plant well known for its medicinal properties. Many species of cannabis are well characterized for their antimicrobial, anti-diabetic and anticancer effects in India and worldwide.
The present review focuses on the various medicinal properties from extracts and the various compounds well isolated and characterized from different varieties of Cannabis plant.
Keywords:
- Cannabis
- anticancer
- marijuana
- antimicrobial
How to Cite
Sonam, ., & Joshi, M. D. (2023). Medicinal Properties in Some Components of Cannabis Species. PLANT CELL BIOTECHNOLOGY AND MOLECULAR BIOLOGY, 24(1-2), 17-22. https://doi.org/10.56557/pcbmb/2023/v24i1-28094
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Caffarel MM, Andradas C, Pérez-Gómez E, Guzmán M, Sánchez C. Cannabinoids:a new hope for breast cancertherapy? Cancer Treat Rev. 2012;38(7):911-8. DOI: 10.1016/j.ctrv.2012.06.005, PMID 22776349.
Rupasinghe HPV, Kumar SK, Murray B, Zheljazkov VD, Zheljazkov VD. Industrial hemp (Cannabis sativa subsp. sativa) as an emerging source for value-added functional food ingredients and nutraceuticals. Molecules. Sep. 2020;25(18):4078. DOI: 10.3390/molecules25184078, PMID 32906622.
Degenhardt L, Coffey C, Carlin JB, Swift W, Moore E, Patton GC. Outcomes of occasional cannabis use in adolescence: 10- year follow-up study in Victoria, Australia. Br J Psychiatry. 2010; 196(4):290-5. DOI: 10.1192/bjp.bp.108.056952, PMID 20357305.
Divashuk MG, Alexandrov OS, Razumova OV, Kirov IV, Karlov GI. Molecular cytogenetic characterization of the dioecious cannabis sativa with an XY chromosome sex determination system. PLos One. 2014;9(1):e85118.
Hillig KW. Genetic evidence for specification in Cannabis (Cannabaceae). Genet. Resour. Crop Evol. 2005;52:161-180.
Faber Taylor A, Kuo F, Sullivan W. views of nature and self-discipline: evidence from inner city children. J. Environ. Psychol. 2002;22:49-63. DOI: 10.1006/jevp.2001.0241
Sibanda T, Okoh AI. The challenges of overcoming antibiotic resistance: plant extracts as potential sources of antimicrobial and resistance modifying agents. Afr. J. Biotechnol. 2007;6:2886-2896.
Taura F, Sirikantaramas S, Shoyama Y, Shoyama Y, Morimoto S. Phytocannabinoids in Cannabis sativa: Recent studies on biosynthetic enzymes. Chem Biodivers. 2007a;4(8):1649–63.
Zirpel B, Stehle F, Kayser O. Production of D9 tetra hydro-cannabinolic acid from cannabigerolic acid by whole cells of Pichia (Komagataella) pastoris expressing D9-tetrahydrocannabinolic acid synthase from Cannabis sativa L. Biotechnol. Lett. 2015;37:1869-1875. DOI:10.1007/s10529-015-1853-x
Russo EB. Taming THC: potential cannabis synergy and phytocannabinoid-terpenoid entourage effects. Br J Pharmacol. 2011;163(7):1344-64. DOI: 10.1111/j.1476-5381.2011.01238.x, PMID 21749363.
Solinas M, Massi P, Cantelmo AR, Cattaneo MG, Cammarota R, Bartolini D, et al. Cannabidiol inhibits angiogenesis by multiple mechanisms. Br J Pharmacol. 2012;167(6):1218-31. DOI: 10.1111/j.1476-5381.2012.02050.x, PMID 22624859.
Sujeeva K. Hettihewa, Yasin Hemar, Vasantha RuPasinghe HP. Comparative study if radical sacvenging activity, antioxidant capacity and phenolic profiles of selected kiwifruit genotypes grown in NewZealand. Int J Recent Sci Res. 2020;11(05):38752-28757.
Żuk-Gołaszewska K, Żuk-Gołaszewska K, Gołaszewski J. Cannabis sativa L.— Cultivation and quality of raw material. J Elem. 2018;23(3/2018):971-84. DOI: 10.5601/jelem.2017.22.3.1500
Grotenhermen F, Müller-Vahl K. Medicinal uses of marijuana and cannabinoids. Crit Rev Plant Sci. 2016;35(5-6):378-405. DOI: 10.1080/07352689.2016.1265360 7.
Velasco G, Sánchez C, Guzmán M. Endocannabinoids and cancer. Handb Exp Pharmacol. 2015;231:449-72. DOI: 10.1007/978-3-319-20825-1_16, PMID 26408171.
Velasco G, Sánchez C, Guzmán M. Anticancer mechanisms of cannabinoids. Curr Oncol. 2016;23(2);Suppl 2:S23-32. DOI: 10.3747/co.23.3080, PMID 27022311.
Demuth DG, Molleman A. Cannabinoid signalling. Life Sci. 2006;78(6):549-63. DOI: 10.1016/j.lfs.2005.05.055, PMID 16109430.
Galve-Roperh I, Sanchez C, Cortes ML, Gomez del pulgar T, Izquierdo M, Guzman M. Anti-tumoral action of cannabinoiods: involvement of sustained ceramide accumulation and extracellular signal-regulated kinase activation. Nat. Med. 2000;6:313-319.
Bifulco M, Malfitano AM, Pistani S, Laezza C. Endocannabinoids in endocrine and related tumours. Endocr. Relat. Cancer. 2008;15:391-408.
Freimuth N, Ramer R, Hinz B. Antitumorigenic effects of cannabinoids beyond apoptosis. J Pharmacol Exp Ther. 2010;332(2):336-44. DOI: 10.1124/jpet.109.157735, PMID 19889794.
Pertwee RG, Ross RA, Craib SJ, Thomas A. (-)-Cannabidiol antagonizes cannabinoid receptor agonists and noradrenaline in the mouse vas deferens. Eur J Pharmacol. 2002;456(1-3):99-106. DOI: 10.1016/s0014-2999(02)02624-9, PMID 12450575.
Thomas A, Stevenson LA, Wease KN, Price MR, Baillie G, Ross RA, et al. Evidence that the plant cannabinoid Δ9- tetrahydrocannabivarin is a cannabinoid CB1 and CB2 receptor antagonist. Br J Pharmacol. 2005;146(7):917-26. DOI: 10.1038/sj.bjp.0706414, PMID 16205722.
Chakravarti B, Ravi J, Ganju RK. Cannabinoids as therapeutic agents in cancer: Current status and future implications. Oncotarget. 2014;5(15):5852- 72. DOI: 10.18632/oncotarget.2233, PMID 25115386.
Hudak J, Ramsey G, Walsh J. Uruguay’s, Cannabis Law: Pioneering a New Paradigm WOLA Centre for Effective Public Management at Brookings. 2018;1–24.
Ramsey G. Uruguay. Marijuana, Organized Crime and the Politics of Drugs InSight Crime. 2013;1-16.
Johnston LD, O’Malley PM, Miech RA, Bachman JG, Schulenberg JE. Overview, key findings on adolescent drug use. Ann Arbor: University of Michigan Institute for Social Research; 2014.
National Survey on Drug Use and Health, 2012 (ICPSR 34933)
Caffarel MM, Andradas C, Pérez-Gómez E, Guzmán M, Sánchez C. Cannabinoids:a new hope for breast cancertherapy? Cancer Treat Rev. 2012;38(7):911-8. DOI: 10.1016/j.ctrv.2012.06.005, PMID 22776349.
Rupasinghe HPV, Kumar SK, Murray B, Zheljazkov VD, Zheljazkov VD. Industrial hemp (Cannabis sativa subsp. sativa) as an emerging source for value-added functional food ingredients and nutraceuticals. Molecules. Sep. 2020;25(18):4078. DOI: 10.3390/molecules25184078, PMID 32906622.
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